منابع مشابه
Spare the (Elastic) Rod
Physicists love emergence. From a welter of complex details about a system's constituents, simple and universal rules sometimes emerge that adequately describe the collective behavior of the components. Even if these rules are not completely universal, they often have only a few relevant parameters, a vast simplification compared to the many that describe the constituents individually. But as V...
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BACKGROUND DNA double-strand break (DSB) repair is crucial for the maintenance of genomic stability, and chromatin organization represents one important factor influencing repair efficiency. Mouse rod photoreceptors with their inverted heterochromatin organization containing a single large chromocenter in the middle of the nucleus provide a unique model system to study DSB repair in heterochrom...
متن کاملDNA Double-Strand Breaks
The activation-induced cytidine deaminase (AID) is required for somatic hypermutation (SHM) and class-switch recombination (CSR) of immunoglobulin (Ig) genes, both of which are associated with DNA double-strand breaks (DSBs). As AID is capable of deaminating deoxy-cytidine (dC) to deoxy-uracil (dU), it might induce nicks (single strand DNA breaks) and also DNA DSBs via a U-DNA glycosylase-media...
متن کاملDouble strand break repair.
DNA double-strand breaks (DSBs) are the most dangerous form of DNA damage and can lead to death, mutation, or malignant transformation. Mammalian cells use three major pathways to repair DSBs: homologous recombination (HR), classical nonhomologous end joining (C-NHEJ), and alternative end joining (A-NHEJ). Cells choose among the pathways by interactions of the pathways with CtIP and 53BP1. HR i...
متن کاملIntegrability of a conducting elastic rod in a magnetic field
We consider the equilibrium equations for a conducting elastic rod placed in a uniform magnetic field, motivated by the problem of electrodynamic space tethers. When expressed in body coordinates the equations are found to sit in a hierarchy of noncanonical Hamiltonian systems involving an increasing number of vector fields. These systems, which include the classical Euler and Kirchhoff rods, a...
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ژورنال
عنوان ژورنال: Archive for Rational Mechanics and Analysis
سال: 2005
ISSN: 0003-9527,1432-0673
DOI: 10.1007/s00205-005-0360-y